Table 4.
Therapeutic apheresis with immunosuppressive agents in recurrent post-transplant focal segmental glomerulosclerosis.
Therapeutic apheresis | Drugs | Subjects | Results | Author [Ref] |
---|---|---|---|---|
PE | – | 25 | PR (n = 11) or CR (n = 7) | Uffing A [128] |
+Cyclophosphamide | 1 | No remission | ||
+Rituximab | 30 | PR (n = 9) or CR (n = 5) | ||
IAS | +Rituximab | 12 Children | PR (n = 2) or CR (n = 8) Two maintained remission without IAS and eight became IAS dependent after 3 months. |
Allard L [122] |
+Rituximab | 7 Patients | PR (n = 6) or CR (n = 1) 12 months after IAS, allograft survival was 100% |
Naciri Bennani H [129] | |
LDL-A | +Methylprednisolone | 7 Children | PR (n = 3) or CR (n = 4) | Shah L [125] |
PE: Plasma exchange; IAS: immunoadsorption; LDL-A: low-density lipoprotein apheresis; PR: partial remission; CR: complete remission.