Table 3.
Pathogens identified in 99 included children.1
| Pathogens | Viral culture n (%) |
BioFire multiplex PCR* n (%) |
Overall n (%) |
|---|---|---|---|
| CSF | |||
| Enterovirus | 11 (11.1) | 62 (62.6) | 66 (66.7) |
| Adenovirus | 1 (1.0) | 1 (1.0) | |
| Enterovirus and mumps virus coinfection | 1 (1.0) | – | 1 (1.0) |
| Herpes simplex virus 1 | 0 (0) | 1 (1.0) | 1 (1.0) |
| Herpes simplex virus 6 | 0 (0) | 1 (1.0) | 1 (1.0) |
| Haemophilus influenzae | – | 1 (1.0) | 1 (1.0) |
|
– | 1 (1.0) | 1 (1.0) |
| At least one pathogen | 13 (13.1) | 66 (66.7) | 72 (72.7) |
| Blood culture | |||
| Burkholderia cepacia | – | – | 1 (1.0) |
| Candida parapsilosis | – | – | 1 (1.0) |
| Staphylococcus aureus | – | – | 2 (2.0) |
| Streptococcus agalactiae | – | – | 1 (1.0) |
| At least one pathogen | – | – | 5 (5.1) |
Notes: *No sample was positive for Neisseria meningitidis, Escherichia coli K1, S. agalactiae, Listeria monocytogenes, herpes simplex virus type 2, cytomegalovirus, varicella zoster virus, human parechovirus, and Cryptococcus neoformans/gattii.
1
Additional real-time PCR tests were performed to identify Dengue virus, two bacteria: (Klebsiella pneumoniae and Staphylococcus aureus), and five main Candida species (C. parapsilosis, C. tropicalis, C. albicans, C. glabrata, and C. rugosa) on supernatant after viral culture. But no sample was positive for these pathogens.
CSF: cerebrospinal fluid; PCR: Polymerase Chain Reaction.