Table 1.
Optical properties of PDs along with binding parameters to PDEδ. 
| Compound | R | *λmax ex
(nm) |
*λmax em (nm) | **Kd value(μM) | **Half-life (min) | ***AlogP |
|---|---|---|---|---|---|---|
| PD1 |
|
430 | 530 | 0.284 ± 0.140 | 36 ± 2 | 5.744 |
| PD3 |
|
440 | 526 | 0.491 ± 0.012 | 41 ± 6 | 5.481 |
| PD4 |
|
430 | 515 | 0.505 ± 0.033 | 31 ± 9 | 4.995 |
| PD5 |
|
430 | 515 | 0.720 ± 0.085 | 20 ± 4 | 4.979 |
| PD6 |
|
430 | 515 | 1.285 ± 0.261 | 19 ± 3 | 4.962 |
| PD7 |
|
430 | 515 | 1.541 ± 0.180 | 14 ± 1 | 5.904 |
| PD8 |
|
430 | 530 | 0.643 ± 0.128 | 35 ± 7 | 5.904 |
| PD25 |
|
440 | 526 | 0.425 ± 0.075 | 26 ± 3 | 4.949 |
*These values represent maximum wavelengths of absorption and emission measured for each compound.
**Data are stated as the mean ± standard deviations (SD) of three independent experiments.
***AlogP was calculated using BIOVIA Discovery Studio 2020.