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. 2022 Jun 14;37(1):1667–1693. doi: 10.1080/14756366.2022.2076675

Table 12.

Representative CRBN-based PROTACs targeting EGFR.

Compounds Target protein Structure Ref.
PROTAC 38 EGFR graphic file with name IENZ_A_2076675_ILG0038_C.jpg 87
PROTAC 39 EGFR graphic file with name IENZ_A_2076675_ILG0039_C.jpg 88
PROTAC 40 EGFR graphic file with name IENZ_A_2076675_ILG0040_C.jpg 89
PROTAC 41 EGFR graphic file with name IENZ_A_2076675_ILG0041_C.jpg 90
PROTAC 42 EGFR graphic file with name IENZ_A_2076675_ILG0042_C.jpg 91
PROTAC 43 EGFR graphic file with name IENZ_A_2076675_ILG0043_C.jpg 91
PROTAC 44 EGFR graphic file with name IENZ_A_2076675_ILG0044_C.jpg 92
PROTAC 45 EGFR graphic file with name IENZ_A_2076675_ILG0045_C.jpg 93