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. 2022 Jun 14;37(1):1667–1693. doi: 10.1080/14756366.2022.2076675

Table 13.

Representative VHL-based PROTACs targeting EGFR.


Compounds		 Target protein Structure Ref.
PROTAC 46 EGFR graphic file with name IENZ_A_2076675_ILG0046_C.jpg 22
PROTAC 47 EGFR graphic file with name IENZ_A_2076675_ILG0047_C.jpg 22
PROTAC 48 EGFR graphic file with name IENZ_A_2076675_ILG0048_C.jpg 22
PROTAC 49 EGFR graphic file with name IENZ_A_2076675_ILG0049_C.jpg 87
PROTAC 50 EGFR graphic file with name IENZ_A_2076675_ILG0050_C.jpg 88
PROTAC 51 EGFR graphic file with name IENZ_A_2076675_ILG0051_C.jpg 94
PROTAC 52 EGFR graphic file with name IENZ_A_2076675_ILG0052_C.jpg 95
PROTAC 53 EGFR graphic file with name IENZ_A_2076675_ILG0053_C.jpg 90
PROTAC 54 EGFR graphic file with name IENZ_A_2076675_ILG0054_C.jpg 96