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. 2022 Jun 14;37(1):1667–1693. doi: 10.1080/14756366.2022.2076675

Table 21.

Representative CRBN-based PROTACs targeting IRAK4.

Compounds Target protein Structure Ref.
PROTAC 77 IRAK4 graphic file with name IENZ_A_2076675_ILG0077_C.jpg 121
PROTAC 78 IRAK4 graphic file with name IENZ_A_2076675_ILG0078_C.jpg 122