Table 8.

The effect of Malva neglecta extract on the liver and renal function tests of diabetic obese rats.

Treatment groups	Urea (mg/dl)	Creatinine (mg/dl)	ALT (U/L)	AST (U/L)	Bilirubin (mg/dl)	Alkaline phosphatase (U/L)
Normal control	31 ± 3.4∗∗∗	0.35 ± 0.06∗∗∗	418 ± 23∗∗∗	140 ± 8∗∗∗	0.41 ± 0.01∗∗∗	723 ± 22∗∗∗
Diseased control	67 ± 2.3	1.05 ± 0.10	1075 ± 43	170 ± 5	0.73 ± 0.02	2483 ± 45
Standard therapy	35 ± 2.6∗∗∗	0.38 ± 0.07∗∗∗	515 ± 31∗∗∗	150 ± 7∗∗∗	0.52 ± 0.04∗∗∗	1487 ± 63∗∗∗
MNME 250 mg/kg	51 ± 4.4∗∗∗	0.81 ± 0.02∗∗	836 ± 21∗∗∗	166 ± 8	0.71 ± 0.03∗	1891 ± 34∗∗∗
MNME 500 mg/kg	45 ± 2.5∗∗∗	0.62 ± 0.07∗∗∗	721 ± 33∗∗∗	161 ± 8∗∗	0.67 ± 0.01∗∗∗	1780 ± 43∗∗∗
MNME 750 mg/kg	39 ± 3.4∗∗∗	0.47 ± 0.03∗∗∗	611 ± 27∗∗∗	154 ± 6∗∗∗	0.61 ± 0.02∗∗∗	1561 ± 41∗∗∗

Data were presented as mean ± standard deviation (n = 6) and evaluated by one-way ANOVA followed by Tukey's test. ∗∗∗P < 0.001, significant values were observed in comparison of treatment groups with the disease control. ALT: alanine aminotransferase; AST: aspartate aminotransferase; MNME: methanolic extract of Malva neglecta.