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. 2022 Jul 15;309:165–171. doi: 10.1016/j.jad.2022.04.065

Table 1.

Demographic and clinical characteristics of participants with and without anxiety disorder diagnoses.

Variable Comorbid anxiety (n = 44) No comorbid-anxiety (n = 57) Test statistics P
Age (mean ± SD) 47.93 ± 12.10 51.63 ± 10.77 t = 1.60 0.11
Gender, n (%)
 Female 30 (29.70) 35 (34.65) χ2 = 0.25 0.62
 Male 14 (13.86) 22 (21.78)
DSM-5 bipolar diagnosis, n (%)
 Bipolar-I 32 (31.68) 49 (48.51) χ2 = 1.97 0.16
 Bipolar-II 12 (11.88) 8 (7.92)
Medication, n (%)
 Medicated 42 (41.58) 56 (55.45) χ2 = 2.00 0.16
 Mood stabilisers 24 (23.76) 41 (40.59) χ2 = 4.45 0.03
 Antipsychotics 27 (26.73) 32 (31.68) χ2 = 0.42 0.52
 Antidepressants 29 (28.71) 29 (28.71) χ2 = 0.00 0.99
 Anxiolytics and Z-drugs 20 (19.80) 21 (20.79) χ2 = 0.02 0.88
AMS score (mean ± SD) 2.64 ± 3.00 3.68 ± 4.01 t = 1.50 0.14
PHQ score (mean ± SD) 10.39 ± 10.13 5.75 ± 7.06 t = 2.59 0.01
BDI score (mean ± SD) 6.93 ± 12.27 5.60 ± 9.14 t = 0.60 0.55
Above PHQ/BDI threshold score,a n (%) 32 (31.68) 28 (27.72) χ2 = 0.27 0.61
Experienced a mood episode during sleep monitoring, n (%) 20 (19.80) 23 (22.77) χ2 = 0.21 0.65

DSM-5, Diagnostic and Statistical Manual of Mental Disorders (5th Edition); AMS, Altman Self-rating Mania Scale; PHQ, Patient Health Questionnaire-9; BDI, Beck Depression Inventory-II.

a

Cut-off thresholds defined for PHQ and BDI questionnaires, with above-threshold scores indicating clinically significant depressive mood symptoms: PHQ ≥ 10; BDI ≥ 11.