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. 2022 Jun 11;25(4):665–677. doi: 10.1007/s10120-022-01309-6

Table 3.

Application of measures by region of the world

Measures Areas (domains/items assessed) Countries where measures are useda
East Asia Non-East Asian countries East Asia and non-East Asian countries combined
Generic
 EuroQol-5 dimension (EQ-5D) [20] Mobility, Self-care, Pain, Usual activities, and Psychological status 12 5 17
 Medical Outcomes Study Short-form (SF36/SF-36) [19]

Physical and Social functioning, Physical and Emotional role limitations, Mental health, Energy, Pain, and General health perceptions

Domains Physical and Mental component summaries

2 1 3
 Spitzer Quality of Life Index [60] Activity, Daily living, Health, Support of family and friends, Outlook 5 0 5
 15D (15-dimensional measure of HRQoL) [61] Breathing, Mental function, Speech, Vison, Mobility, Usual activities, Vitality, Hearing, Eating, Elimination, Sleeping, Distress, Discomfort and symptoms, Sexual activity, Depression 1 0 1
 World Health Organisation—Quality of Life WHOQOL Scale (also including WHOQOL-BREF) [62] Physical health, Psychological health, Social relationships, Environmental health, 1 3 4
Generic cancer
 European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Core 30 (QLQ-C30) [22]

Domains: Physical functioning, Emotional functioning, Social functioning, Role functioning, Cognitive functioning. Items:

Fatigue, Pain, Nausea/Vomiting, Constipation, Diarrhoea, Insomnia, Dyspnoea, Appetite loss, Financial Difficulties, Global health, Global quality of life

108 51 159
 Functional Assessment of Cancer Therapy—General (FACT-G) [21] Physical well-being, Social/Family well-being, Emotional well-being 2 3 5
 Functional Assessment of Cancer Therapy: Fatigue (FACT-F) [50] Fatigue 0 1 1
 Quality of Life Questionnaire for Cancer Patients treated with anticancer drugs (QOL ACD) [27] Daily Activities, Physical condition, Social activities, Mental status, Psychological status
 Functional Living Index-Emesis (FLIE) [51]

Nausea

Vomiting

2 0 2
Gastric Cancer-specific
 European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire—Gastric Cancer (QLQ-STO22) [23, 24]

Domains: Dysphagia, Dietary restriction, Pain, Reflux, Anxiety

Items: Disease symptoms, treatment side effects, Dry mouth, Body image, taste problems

72 18 90
 Functional Assessment of Cancer Therapy—Gastric Cancer (FACT-Ga) [25]

Gastric cancer subscale items:

Weight loss, Appetite loss, Reflux, Dietary restrictions, Pain/discomfort when eating, Feeling full/heavy in the stomach, Stomach swelling/cramps, Dysphagia, Change in eating habits, Enjoyment of meals (socially), Interference of usual activities, Avoidance of going out, Worry over stomach problems, Discomfort/pain in stomach area, Flatulence, Diarrhoea, Fatigue, Weakness, Plans for the future

3 4 7
 GC-PROM: Patient-reported outcome measure for Chinese patients with gastric cancer [55] Physical: Abdominal symptoms, Systemic symptoms, Physical state, Independence; Psychological: Anxiety, Depressed, Pessimism; Social: Social support, Social adaptation; Therapeutic: Effectiveness, Satisfaction, Compliance, Drug side effects 1 0 1
KOQUSS-40: Symptom-Focused Quality of Life Questionnaire for Gastric Cancer Patients after Gastrectomy [45] General quality of life, Indigestion, Dysphagia, Reflux, Dumping syndrome, Bowel habit change, Constipation, Psychological factors, Worry about cancer, Scar problems, Financial problems 1 0 0
 Korenaga’s Score Scale/Chew wun Wu special symptom score [56, 57]

Appetite, Consistency of digested food, Volume of digested food, Frequency of eating, Eating time, Postprandial abdominal

fullness, Heartburn, Diarrhea, and Constipation persistence, Insomnia, Body weight changes, Swallowing problems, Vomiting, Dizziness

2 1 3
 Post-gastrectomy Syndrome Assessment Scale-45/037 (PGSAS45/PGSAS37) [27] In addition to items from the SF-8 and GSRS: PGSAS-specific items: Bile regurgitation, sense of food sticking, Postprandial fullness, Early satiation, Lower abdominal pains, Dumping (early and late) symptoms. Dietary intake (amount and quality of ingestion), Work, Satisfaction with daily life 2 2 4
 System of Quality of Life Instruments for Cancer Patients: Stomach Cancer (QLICP-ST) [28] Physical, Psychological, Common symptoms and side effects 1 0 1
Quality of life assessment based on Traditional Chinese Medicine for advanced gastric cancer (QLASTCM-Ga) [58]

Unity of the body and spirit

Correspondence between man and universe

Specific module

General module

1 0 1
Oesophageal-specific
 European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire—Oesophago-Gastric Modules (OG25) [46] Domains: Dysphagia, Eating restrictions, Reflux, Odynophagia, Pain, Anxiety 3 2 5
 European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire – Oesophageal Cancer (OES18) [47] Domains: Dysphagia, Eating, Reflux, Pain. Items: Saliva swallowing, Choking, Dry mouth, Taste, Coughing, Talking 3 1 4
Gastrointestinal-specific
 Gastrointestinal Quality of Life Index (GLQI) [26] Gastrointestinal symptoms, Emotion, Physical function, Social function, Medical treatment 1 5 6
 Gastrointestinal Symptom Rating Scale (GSRS) [48] Reflux, Abdominal pain, Indigestion, Diarrhoea, Constipation 5 1 6
 Patient Assessment of Gastrointestinal Disorders-Symptoms Severity Index (PAGI-SYM) [49] Heartburn/regurgitation, Nausea/vomiting, Fullness/early satiety, Bloating, Upper abdominal pain, Lower abdominal pain 1 0 1
 Gastroesophageal reflux disease (GERD)-QOL Questionnaires [59] Daily activity, Diet, Psychological well-being 1 1 2
Bespoke questions developed for the purpose of the study

Post-gastrectomy symptoms

Dumping syndrome symptoms

Satisfaction

Psychological functioning

Social functioning

16 4 20

aStudies often use more than one measure