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. 2022 Jun 23;12:9950. doi: 10.1038/s41598-022-13495-5

Table 3.

Study methodological strengths and limitations.

No of studies (N = 21) Prevalence (%)
Study methodological strength
COVID cases lab confirmed (PCR or antibody) 21 100
More than 100 COVID patients 14 66.66
Timing of COVID well specified 14 66.66
Long COVID defined > 3 months 8 38.10
Point in time specific and well defined 10 42.11
Control added 8 31.60
Control group with negative antibody test 2 10.50
Clinical assessment (not self/parent reported) 7 36.84
New symptoms on or after COVID 6 31.58
Specify if persistent symptom or if it is symptoms months after acute COVID 2 9.52
Exclude vaccinated/no vaccinated in sample 4 19.05
Duration (end) of symptoms specified 3 14.29
Validated questionnaires or clinical evaluation for symptoms 5 23.81
Bias
Low chance of recall bias 7 33.33
Low chance of selection bias 4 19.05
Low chance of misclassification bias 3 14.29
Low chance of nonresponse bias/loss of follow up 3 14.29
Stratifications
Stratify by severity/only one severity 4 19.05
Stratified by age/only one age group studied 6 28.57
Stratified by preexisting medical conditions 1 4.76
Stratified by sex 2 9.52
Stratify by vaccination status 0 0