Table 1.
Basic clinical features of patients from each age-onset group.
| All (n = 797) |
JSLEa (n = 88) |
ASLEb (n = 638) |
LSLEc (n = 71) |
P | |
|---|---|---|---|---|---|
| Age of diagnosis (years) | 32.6 ± 12.5 | 15.4 ± 2.2 | 32.0 ± 8.3 | 59.0 ± 6.7 | < 0.001 |
| Female (%) | 737 (92.5) | 79 (89.8) | 593 (92.9) | 65 (91.5) | 0.545 |
| Clinical features at diagnosis | |||||
| Malar rash (%) | 527 (66.1) | 67 (76.1) | 422 (66.1) | 38 (53.5) | 0.011 |
| Discoid rash (%) | 50 (6.3) | 7 (8.0) | 37 (5.8) | 6 (8.5) | 0.538 |
| Photosensitivity (%) | 205 (25.7) | 23 (26.1) | 168 (26.3) | 14 (19.7) | 0.479 |
| Oral ulcer (%) | 156 (19.6) | 17 (19.3) | 126 (19.7) | 13 (18.3) | 0.957 |
| Arthritis (%) | 530 (66.5) | 54 (61.4) | 430 (67.4) | 46 (64.8) | 0.505 |
| Serositis (%) | 157 (19.7) | 12 (13.6) | 128 (20.1) | 17 (23.9) | 0.234 |
|
Renal disorder (%) |
698 (87.6) | 79 (89.8) | 557 (87.3) | 62 (87.3) | 0.803 |
|
CNSd disorder (%) |
30 (3.8) | 4 (4.5) | 24 (3.8) | 2 (2.8) | 0.850 |
|
Hematologic disorder (%) |
477 (59.8) | 54 (61.4) | 386 (60.5) | 37 (52.1) | 0.374 |
|
Immunologic disorder (%) |
514 (64.5) | 51 (58.0) | 417 (65.4) | 46 (64.8) | 0.395 |
|
ANAe positive (%) |
649 (81.4) | 75 (85.2) | 518 (81.2) | 56 (78.9) | 0.557 |
|
SLEDAI-2Kf on admission |
16.26 ± 8.168 | 17.43 ± 9.139 | 16.34 ± 8.163 | 14.08 ± 6.474 | 0.031 |
| SDIg on admission | 114 (14.3) | 12 (13.6) | 88 (13.8) | 14 (19.7) | 0.393 |
aJSLE juvenile-onset SLE; bASLE adult-onset SLE; cLSLE late-onset SLE; dCNS central nervous system; eANA antinuclear antibody; fSLEDAI-2 K SLE Disease Activity Index 2000; gSDI Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index.