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. 2022 Jun 23;12:10683. doi: 10.1038/s41598-022-14840-4

Table 4.

Laboratory findings among different age-onset groups.

Lab results
on admission
All
(n = 797)
JSLEa
(n = 88)
ASLEb
(n = 638)
LSLEc
(n = 71)
P
Leukopenia (%) 389 (48.8) 34 (38.6) 318 (49.8) 37 (52.1) 0.121
Erythropenia (%) 330 (41.4) 33 (37.5) 267 (41.8) 30 (42.3) 0.731
Thrombocytopenia (%) 231 (29.0) 25 (28.4) 180 (28.2) 26 (36.6) 0.331
Anaemia (%) 509 (63.9) 57 (64.8) 410 (64.3) 42 (59.2) 0.685
Proteinuria (%) 433 (54.3) 48 (54.5) 359 (56.3) 26 (36.6) 0.007
Haematuria (%) 326 (40.9) 38 (43.2) 268 (42.0) 20 (28.2) 0.072
Increased ALTd (%) 124 (15.6) 19 (21.6) 98 (15.4) 7 (9.9) 0.122
Increased ASTe (%) 138 (17.3) 17 (19.3) 112 (17.6) 9 (12.7) 0.512
Hypoalbuminemia (%) 457 (57.3) 41 (46.6) 382 (59.9) 34 (47.9) 0.015
Increased serum creatinine (%) 101 (12.7) 12 (13.6) 86 (13.5) 3 (4.2) 0.081
Increased BUNf (%) 184 (23.1) 22 (25.0) 146 (22.9) 16 (22.5) 0.901
Decreased eGFRg (%) 72 (9.0) 6 (6.8) 61 (9.6) 5 (7.0) 0.582
Increased ESRh (%) 592 (74.3) 60 (68.2) 476 (74.6) 56 (78.9) 0.282
Positive ANA i (%) 708 (88.8) 78 (88.6) 566 (88.7) 64 (90.1) 0.935
Positive anti-dsDNAj(%) 411 (51.6) 47 (53.4) 332 (52.0) 32 (45.1) 0.503
Positive anti-Smk (%) 256 (32.1) 35 (39.8) 202 (31.7) 19 (26.8) 0.186
Decreased complement C3 (%) 552 (69.3) 66 (75.0) 442 (69.3) 44 (62.0) 0.209
Decreased complement C4 (%) 464 (58.2) 60 (68.2) 363 (56.9) 41 (57.7) 0.132

aJSLE juvenile-onset SLE; bASLE adult-onset SLE; cLSLE late-onset SLE; dALT alanine aminotransferase; eAST aspartate aminotransferase; fBUN blood urea nitrogen; geGFR estimated glomerular filtration rate; hESR erythrocyte sedimentation rate; iANA, anti-nuclear antibody; janti-dsDNA anti-double-stranded deoxyribonucleic acid antibody; kanti-Sm anti-Smith antibody.