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. 2022 Jun 23;13(6):566. doi: 10.1038/s41419-022-05015-0

Table 1.

The clinical characteristic and ASNS level in non-small cell lung-cancer patients (N = 92).

Characteristic COX regression model
P* HR(95%CI)
Age (30–84 years) 0.781 1.079 (0.63,1.85)
30–50(9,10%)
50–70(61,66%)
70–84(23,24%)
Sex male(49,53%) 0.524 1.202 (0.682,2.117)
female(43,47%)
Pathological degree I–III 0.527 0.840 (0.491,1.44)
I(3,3%); II(61,66%);III(28,31%)
Tumor size (1.5–14 cm) 0.416 1.183 (0.788,1.776)
1.5–3.0(18,20%)
3.0–4.5(45,49%)
≥4.5(29,31%)
lymph invasion positive(58,63%) 0.806 0.897 (0.375,2.145)
negative(34,37%)
Clinical stages I–IV 0.001 2.081 (1.343,3.224)
I(28,30%); II(17,18%);III(47,52,%)
ASNS expression** cancer tissue (IHC score)
in nuclues 83%low(117 ± 57); 17%high(330 ± 77) 0.014 3.837 (1.313,11.214)
in cytoplasm 68%low(131 ± 33); 32%high(297 ± 60) 0.065 2.114 (0.954,4.683)
para-cancer tissue (IHC score)
in nuclues 65%low(92 ± 23); 35%high(180 ± 42) 0.686 1.262 (0.41,3.885)
in cytoplasm 60%low(77 ± 13); 40%high(124 ± 26) 0.237 0.473 (0.137,1.635)

*P-value was calculated by COX regression model;

**ASNS expression were detected by immunohistochemistry.