Table 1.
The clinical characteristic and ASNS level in non-small cell lung-cancer patients (N = 92).
Characteristic | COX regression model | |||
---|---|---|---|---|
P* | HR(95%CI) | |||
Age | (30–84 years) | 0.781 | 1.079 (0.63,1.85) | |
30–50(9,10%) | ||||
50–70(61,66%) | ||||
70–84(23,24%) | ||||
Sex | male(49,53%) | 0.524 | 1.202 (0.682,2.117) | |
female(43,47%) | ||||
Pathological degree | I–III | 0.527 | 0.840 (0.491,1.44) | |
I(3,3%); II(61,66%);III(28,31%) | ||||
Tumor size | (1.5–14 cm) | 0.416 | 1.183 (0.788,1.776) | |
1.5–3.0(18,20%) | ||||
3.0–4.5(45,49%) | ||||
≥4.5(29,31%) | ||||
lymph invasion | positive(58,63%) | 0.806 | 0.897 (0.375,2.145) | |
negative(34,37%) | ||||
Clinical stages | I–IV | 0.001 | 2.081 (1.343,3.224) | |
I(28,30%); II(17,18%);III(47,52,%) | ||||
ASNS expression** | cancer tissue (IHC score) | |||
in nuclues | 83%low(117 ± 57); 17%high(330 ± 77) | 0.014 | 3.837 (1.313,11.214) | |
in cytoplasm | 68%low(131 ± 33); 32%high(297 ± 60) | 0.065 | 2.114 (0.954,4.683) | |
para-cancer tissue (IHC score) | ||||
in nuclues | 65%low(92 ± 23); 35%high(180 ± 42) | 0.686 | 1.262 (0.41,3.885) | |
in cytoplasm | 60%low(77 ± 13); 40%high(124 ± 26) | 0.237 | 0.473 (0.137,1.635) |
*P-value was calculated by COX regression model;
**ASNS expression were detected by immunohistochemistry.