Table 1.

Binding affinities of the RNA aptamers for RRM1 and RRM1-2.

	Kd screening (µM)
	RRM1	RRM1-2
	0.58 ± 0.01	0.10 ± 0.01
	1.44 ± 0.40	0.75 ± 0.15
	0.90 ± 0.20	0.65 ± 0.12
	0.90 ± 0.35	1.30 ± 0.45
	1.65 ± 0.30	1.50 ± 0.30
	2.50 ± 0.65	1.60 ± 0.40

K_d values of candidate RNA aptamers interactions with the isolated RRM1 of TDP-43 (second column) and RRM1-2 (third column; mean ± S.D.; n = 3).