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. 2020 Oct 27;13(7):513–531. doi: 10.1007/s13238-020-00795-7

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Gene expression profiling after twenty-three pesticides exposure. (A) Number of differential expression genes (DEGs) after each pesticide treatment. (B) Pesticides clusters using the combined 7991 DEGs. (C) The heatmap of 107 DGEs of FAW cytochrome P450 genes. X axial shows the different treatment (P1–P23), the color shows the fold change of DGEs, yellow means up regulation, blue means down regulation, black means the gene is not DEG in one/some treatment(s). (D) DGEs of Bt involved in hsa00982 pathway. The red means up-regulated DEGs, the blue means down-regulated DEGs