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. 2022 Jun 23;10:16. doi: 10.1186/s40345-022-00262-8

Table 3.

Clinical variables of the bipolar patient groups

BP-acute-D
(N = 20)
BP-euth-D
(N = 19)
BP-euth-M
(N = 13)
χ2 p Post-hoc χ2 tests with Bonferroni-correction
Bipolar Typea 5.87 .053
 Type I 8 (44%) 9 (47%) 11 (85%)
 Type II 10 (56%) 10 (53%) 2 (15%)
Age of onset of diseaseb 28.2 (12.5) 27.8 (11.0) 29.1 (10.8) .16 .926
Number of inpatient staysc 4.6 (6.2) 3.1 (2.3) 3.5 (2.9) .99 .611
Medicationd
Antidepressants 19 (95%) 12 (63%) 6 (46%) 10.1 .006** BP-acute-D > BP-euth-M (χ2 = 10.236, p = .009)
Lithium 11 (55%) 12 (63%) 9 (69%) .71 .702
Valproate 5 (25%) 4 (21%) 3 (23%) .20 1
Pregabalin 2 (10%) 1 (5%) 1 (8%) .57 1
Lamotrigine 3 (15%) 1 (5%) 1 (8%) 1.10 .837
Antipsychotics 18 (90%) 7 (37%) 10 (77%) 13.2 .001** BP-acute-D > BP-euth-D (χ2 = 11.965, p = .003)
Benzodiazepines 2 (10%) 3 (16%) - .29 .661

BP-acute-D patients in an acute depressive phase, BP-euth-D euthymic patients with a predominant depressive polarity, BP-euth-M euthymic patients with a predominant manic polarity

aNumber and percentage of patients (for two patients of the BP-acute-D group the information about the bipolar type was not available)

bMean age and SD (for one patient of the BP-acute-D group the information about the age of onset of disease was not available)

cN and SD

dNumber and percentage of patients

**p<0.01