TABLE 4.

Donor-related reasons for disqualification from the LKD program.

Medical n (%)	n = 139
mGFR < 70 mL/min/1.73 m2#	42 (30.2)
Nephrological*	14 (10.1)
Urological**	12 (8.6)
Cardiovascular risk factors
Hypertension (poorly controlled with more than two medications)	17 (12.9)
Diabetes or pathological oGTT	14 (10.1)
Smoking	9 (6.5)
Arteriosclerosis	6 (4.3)
BMI > 35 kg/m2 (without weight loss in the work-up)	23 (16.5)
Age (too young)	7 (5.0)
Malignancy	28 (20.1)
In recent past medical history	7 (5.0)
Diagnosed during work-up	21 (15.1)
Psychiatric	7 (5.0)
Lung disease	4 (2.9)
Genetical predisposition for kidney disease	3 (2.2)
Active infectious disease (Hepatitis B/C, TBC, or HIV)	4 (2.9)
Other***	5 (3.6)
Psychosocial n (%)	n = 41
Psychological assessment	10 (24.3)
Insufficient bond between donor and recipient	5 (12.2)
Other social aspects****	15 (36.5)
Uncertainty for transplantation	5 (12.2)
Signs of coercion	2 (4.9)
Financial problems	6 (14.6)
Non-adherence	4 (9.8)
Religion	2 (4.9)
Immunological§ n (%)	n = 52
Positive crossmatch	21 (40.4)
Donor specific HLA Antibodies	31 (59.6)

^#As assessed by renal nuclear scan. *Includes incidental unclear microhematuria and/or proteinuria, newly diagnosed kidney disease (e.g., Alport syndrome). **Includes incidental abnormal kidney cysts, abnormal kidney vessels or ureter, unclear incidental macrohematuria and/or nephrolithiasis or high risk for nephrolithiasis. ***Includes neurological abnormalities (newly diagnosed multiple sclerosis), one case of Merkelsson-Rosenthal Syndrome, and gastrointestinal abnormalities. ****Includes difficult social circumstances such as single parents of small children, planning child conception. Some candidates qualified for more than one category. n, number; mGFR, measured glomerular filtration rate; oGTT, oral glucose tolerance test; HIV, Human immunodeficiency virus; HLA, human leucocyte antigen; TBC, tuberculosis.

^§donor-related contraindications depending on the potential recipient.