Table 3.
Comparison of the related characteristics of thyroid nodule for diagnosis by SWE.
| Malignant nodules n(%) | Benign nodules n(%) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| False negative (n=88)Emax ≤ 36.15Kpa | True positive(n=235) | Statistics | P | False positive(n=22) | True negative(n=90) | Statistics | p | ||
| Emax>36.15 Kpa | Emax>36.15 Kpa | Emax ≤ 36.15Kpa | |||||||
| Gender | Female | 71(80.7) | 184(78.3) | χ2 = 0.219 | 0.64 | 17(77.3) | 71 (78.9) | χ2 = 3.696 | 0.055 |
| Age | (year) | 46.8 ± 8.2 | 45.7 ± 10.5 | t=-0.894 | 0.372 | 53.3 ± 10.4 | 53.4 ± 10.5 | t=0.019 | 0.985 |
| The largest diameter | (cm) | 0.60 (0.40, 0.80) | 0.90(0.70, 1.50) | Z=-6.989 | <0.001 | 1.55 (0.98, 2.15) | 0.80 (0.60, 1.33) | Z=-3.029 | 0.002 |
| Nodule size | <1cm | 78 (88.6) | 132(56.2) | χ2 = 31.072 | <0.001 | 6 (27.3) | 52 (57.8) | χ2 = 9.599 | 0.007 |
| 1cm-2cm | 10 (11.4) | 76 (32.3) | 8 (36.4) | 28 (31.1) | |||||
| >2cm | 0 (0) | 27 (11.5) | 8 (36.4) | 10 (11.1) | |||||
| Structure | Spongy | 0 (0) | 0 (0) | χ2 = 0.006 | 0.936 | 0 (0) | 5 (5.6) | χ2 = 2.480 | 0.249 |
| Solid-cystic | 2 (2.3) | 5(2.1) | 2 (9.1) | 19 (21.1) | |||||
| Solid | 86 (97.7) | 230 (97.9) | 20 (90.9) | 66 (73.3) | |||||
| Echo | Echo or hyperechoic | 3 (3.4) | 14 (6.0) | χ2 = 1.263 | 0.545 | 10 (45.5) | 54 (60.0) | χ2 = 1.527 | 0.217 |
| Hypoechoic | 81 (92.0) | 214 (91.0) | 12 (54.5) | 36 (40.0) | |||||
| Extremely hypoechoic | 4(4.6) | 7 (3.0 | 0 (0) | 0 (0) | |||||
| Edge | Smooth | 21 (23.9) | 29 (12.3) | χ2 = 15.603 | <0.001 | 15 (68.2) | 80 (88.9) | χ2 = 4.839 | 0.036 |
| Irregular | 67 (76.1) | 179 (76.2) | 7 (31.8) | 10 (11.1) | |||||
| Extrathyroidal invasion | 0 (0) | 27 (11.5) | 0 (0) | 0 (0) | |||||
| Anteroposterior/transverse diameter ratio | <1 | 28 (31.8) | 105 (44.7) | χ2 = 4.373 | 0.037 | 21 (95.5) | 81 (90.0) | χ2 = 0.150 | 0.699 |
| >1 | 60(68.2) | 130 (55.3) | 1 (4.5) | 9 (10.0) | |||||
| Calcification | Without calcification | 57 (64.8) | 88 (37.4) | χ2 = 20.634 | <0.001 | 12 (54.5) | 78 (86.7) | χ2 = 10.671 | 0.004 |
| Coarse calcification | 9 (10.2) | 27 (11.5) | 4 (18.2) | 5 (5.5) | |||||
| scattered hyperechoic foci | 22 (25.0) | 120 (51.1) | 6 (27.3) | 7 (7.8) | |||||
| TI-RADS classification | Class 1 | 0 (0) | 0 (0) | χ2 = 6.904 | 0.053 | 0 (0) | 5 (5.6) | χ2 = 10.526 | 0.021 |
| Class 2 | 1 (1.1) | 1 (0.4) | 1 (4.5) | 12 (13.3) | |||||
| Class 3 | 2 (2.3) | 1 (0.4) | 4 (18.2) | 37 (41.1) | |||||
| Class 4 | 17 (19.3) | 27 (11.5) | 10 (45.5) | 27 (30.0) | |||||
| Class 5 | 68 (77.3) | 206 (87.7) | 7 (31.8) | 9 (10.0) | |||||