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. 2022 Jun 10;13:873787. doi: 10.3389/fimmu.2022.873787

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Copyright © 2022 Zhong, Zhang, Hong, Zeng, Chen, Liao, Cai, Xu, Wang, Liu, Tang and Dai

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification and Validation of the Diagnostic Biomarkers for SLE. (A, B) LASSO logistic regression and SVM-RFE algorithm screening diagnostic biomarkers for SLE. (C) The Venn diagram showing the intersection of the diagnostic biomarkers screened by the two algorithms. (D–I) Validation of the expression of diagnostic biomarkers based on the validate data set including GSE4588, GSE50772, GSE99967, and GSE24706. “Con” represented the control samples, and “SLE” represented the SLE patients.