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. 2022 Jun 22;12(6):e059046. doi: 10.1136/bmjopen-2021-059046

Table 1.

Patient characteristics by acute kidney injury (AKI) status at intensive care unit (ICU) admission

Patient demographics All patients
(N=361)
Missing data (no. of patients) AKI
(n=114)
No AKI
(n=242)
P value
(AKI vs no AKI)
Age in years, median (IQR) 63.6 (53.5–72.5) 65.6 (58.4–73.6) 61.6 (52.0–72.3) 0.003
Male 261 (72.3%) 86 (75.4%) 172 (71.1%) 0.233
Female 100 (27.7%) 28 (24.6%) 70 (28.9%) 0.233
BMI, median (IQR) 27.7 (24.8–32.0) 141 27.3 (23.0–30.6) 28.3 (25.1–32.4) 0.132
BMI>30 83 (37.7%) 141 21 (31.8%) 61 (40.4%) 0.147
Current smoker 9 (2.5%) 3 (2.6%) 6 (2.5%) 0.592
Comorbidity/ies 246 (68.1%) 81 (71.1%) 161 (66.5%) 0.233
 1 141 (39.1%) 44 (38.6%) 94 (38.8%) 0.530
>2 105 (29.1%) 37 (32.5%) 67 (27.7%) 0.212
CVD 158 (43.8%) 58 (50.9%) 98 (40.5%) 0.042
DM 74 (20.5%) 23 (20.2%) 50 (20.7%) 0.518
Asthma 55 (15.2%) 15 (13.2%) 39 (16.1%) 0.288
CPD 37 (10.2%) 14 (12.3%) 23 (9.5%) 0.266
Immunocompromised 20 (5.5%) 5 (4.4%) 14 (5.8%) 0.394
Cancer 17 (4.7%) 6 (5.3%) 11 (4.5%) 0.476
CND 12 (3.3%) 5 (4.4%) 7 (2.9%) 0.329
Liver disease 3 (0.8%) 1 (0.9%) 2 (0.8%) 0.687
ACEi/ARB 83 (23.4%) 7 34 (30.6%) 47 (19.7%) 0.019

ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker; BMI, body mass index; CND, chronic neurological disease; CPD, chronic pulmonary disease; CVD, cardiovascular disease; DM, diabetes mellitus.