Table 2.
Dissociation constants (Kd) of MutL WT and mutant versions for 3′ resected DNA ends
| AMPPNP | ATP | |
|---|---|---|
| MutLWT | 0.29 ± 0.12 μM | 0.64 ± 0.32 μM |
| MutLH270A | 1.59 ± 0.23 μM | n.d. |
| MutLH319A | 4.51 ± 1.18 μM | n.d. |
| MutLH270A + H319A | n.d. | n.d. |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.