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. 2022 Jun 3;50(11):6067–6083. doi: 10.1093/nar/gkac475

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© The Author(s) 2022. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — Human box C/D snoRNAs are predicted to target the SARS-CoV-2 transcriptome. (A) Distribution of the number of predicted interactions per snoRNA across the SARS-CoV-2 transcriptome. Human box C/D snoRNAs have a median of 22 predicted interactions having at least 3 consecutive windows with a score greater or equal to 0.85 with SARS-CoV-2 transcriptome. (B) The validated interaction between African green monkey SNORD27 and SARS-CoV-2 is also predicted with human SNORD27. The validated interaction is shown in red, the nucleotide that differs between the African green monkey and human SNORD27 is underlined. The predicted interaction is outlined by the box.