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. 2022 Jun 10;9:902171. doi: 10.3389/fmed.2022.902171

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Copyright © 2022 Liu, Yang, Yang, Xie, Liu, Zhang, Ye, Jiang, Zhang and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Imaging characteristics of calciphylaxis. (A–C) Both CT and X-ray reveal subcutaneous extravascular diffuse calcium deposition of patients with calciphylaxis (yellow arrows, shown as white). (D–F) Bone scintigraphy shows the increased uptake of radiotracer by subcutaneous soft tissues of three calciphylaxis patients, especially the continuous linear abnormal radioactive concentration in the lower limbs (red arrows, shown as black). (G) Diffuse uptake enhancement is also observed with bone scintigraphy when calciphylaxis involves internal organs such as the lungs (blue arrows).