FIG. 1.

Glucose metabolism in an ALDB-deficient mutant of L. lactis overproducing the NOX enzyme. The rerouted pathways are highlighted in grey. Reactions or pathways producing NADH have large black arrows, those that are NADH independent have large white arrows, and those producing NAD⁺ have thin black arrows. The chemical oxidative decarboxylation of α-AL into diacetyl is displayed by a dotted arrow. ACK, acetate kinase; ADH, alcohol dehydrogenase; A/DR, acetoin/diacetyl reductase; PDHC, pyruvate dehydrogenase complex; PTA, phosphotransacetylase.