Table 3.

Age-related subgroup analysis for overall mortality between active surveillance/watchful waiting and focal therapy

Age at diagnosis (year)	Treatment	Patients (n)	HR (95% CI)	P
<60	AS/WW	5070	Reference
	Focal therapy	110	1.65 (0.52–5.27)	0.394
≥60 and <80	AS/WW	13 215	Reference
	Focal therapy	539	1.62 (1.17–2.23)	0.003
≥80	AS/WW	326	Reference
	Focal therapy	32	1.08 (0.43–2.72)	0.868

OM: overall mortality; AS: active surveillance; WW: watchful waiting; HR: hazard ratio; CI: confidence interval