Domain	Judgment	Quotes/comments
Selection bias
Adequate sequence generation Was the allocation sequence adequately generated?	High  Low   Unclear
Allocation concealment
Was allocation adequately concealed	High   Low   Unclear
Performance Bias
Blinding of participants/providers Was knowledge of the allocated interventions adequately prevented during the study	High   Low  Unclear
Detection Bias
Blinding of outcome assessors Was knowledge of the allocated interventions adequately prevented during measurement?	High   Low  Unclear
Attrition bias
Incomplete outcome data addressed Were incomplete outcome data adequately addressed?	High  Low   Unclear
Reporting bias
Free of selective reporting Are reports of the study free of suggestion of selective outcomes reporting?	High   Low   Unclear
Other bias
Free of other bias Was the study apparently free of other problems that could put it at high risk of bias	High   Low   Unclear