FIGURE 1.

Common gray matter (GM) deficits in major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SZ). (A,B) Reduced GMVs were found in the medial orbitofrontal cortex (OFC) across three mental disorders. AFNI’s AlphaSim was used for multiple comparisons corrections; (C) GMVs in medial OFC were correlated with digit symbol substitution test across four groups and PANSS positive scales in patients with SZ.