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. 2022 Jun 10;16:919272. doi: 10.3389/fnins.2022.919272

TABLE 1.

Demographic characteristics of the participants.

MDD (n = 85) BD (n = 42) SZ (n = 70) HC (n = 95) F2-values P-values
Male (%) 40.0 54.8 44.3 49.5 1.09 0.350
Age (years) 32.44 (8.79) 32.88 (8.79) 28.40 (4.92)a 30.21 (6.85) 5.15 0.002*
Education (years) 11.5 (3.60)
(n = 84)
10.5 (3.83)
(n = 40)
11.48 (2.76)
(n = 64)
13.80 (2.88)
(n = 94)
13.89 <0.001
Age of onset (years) 29.18 (9.32)
(n = 84)
26.25 (8.88)
(n = 40)
24.54 (4.86)
(n = 64)
N/A 6.61 0.002
Medication (Yes/No) 66/19 37/5 44/26 N/A 9.55 0.008
Antipsychotics (Yes) 5 24 44 N/A 62.66 <0.001
Antidepressants (Yes) 64 15 0 N/A 91.03 <0.001
Mood stabilizer 1 24 0 N/A 95.25 <0.001
Duration of illness (months) 40.81 (55.87)
(n = 84)
77.10 (77.16)
(n = 40)
43.26 (43.28)
(n = 64)
N/A 5.89 0.003
Digit symbol 48.56 (13.40)
(n = 81)
47.53 (15.25)
(n = 40)
38.18 (10.47)
(n = 57)
62.31 (11.92)
(n = 94)
11.6 <0.001
BDI 18.60 (7.66)
(n = 68)
9.95 (11.71)
(n = 40)
N/A N/A 21.55 <0.001
BAI 42.83 (11.41)
(n = 48)
31.85 (13.75)
(n = 39)
N/A N/A 16.59 <0.001
PANSS total N/A N/A 78.5 (18.15) N/A N/A N/A
PANSS positive N/A N/A 22.74 (3.75) N/A N/A N/A
PANSS negative N/A N/A 19.86 (5.29) N/A N/A N/A

Values are mean (SD) unless otherwise indicated.

BAI, Beck Anxiety Inventory; BD, bipolar disorder; BDI, Beck Depression Inventory; HC, healthy control; MDD, major depressive disorder; N/A, not applicable; PANSS, Positive and Negative Syndrome Scale; SZ, schizophrenia.

*SZ had significantly younger age in years than BD and MDD. No significant differences were found in age or gender between three mental disorders (MDD, BD, and SZ) and HC.