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. 2022 Jun 22;9(1):e000660. doi: 10.1136/lupus-2022-000660

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Correlations of peripheral T lymphocyte phenotypes with disease activity and autoantibody titre in patients with SLE. (A) The frequency of CD4⁺CXCR5⁻PD1⁺ T cells was associated with SLEDAI-2K scores. (B) The frequency of terminally differentiated CD8⁺ T cells was associated with the level of C4. The frequency of CD8⁺CD38⁺HLADR⁺ T cells was associated with the levels of C3 (C), ANA (D) and anti-dsDNA (E). Correlations of peripheral T lymphocyte phenotypes with disease activity and autoantibody titre were assessed using Spearman’s rank correlation coefficient. anti-dsDNA, antidouble-stranded DNA; C3, complement 3; C4, complement 4.