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. 2022 Jun 8;14(6):1220. doi: 10.3390/pharmaceutics14061220

Table 3.

Multivariable analysis and risk scoring system for ritodrine-induced adverse events.

Parameters Crude Odds Ratio Adjusted Odds Ratio Score
Age ≥ 35 years 1.43 (0.59–3.49) 1.90 (0.69–5.27)
Gestational age < 30 weeks 1.41 (0.71–2.80) 1.66 (0.79–3.49)
Height < 160 cm 2.54 (1.25–5.17) * 2.41 (1.13–5.12) * 0, 1 a
GNAS rs7121 0.60 (0.36–0.99) * 1.00 (0.51–1.97)
GNAS rs3730168 2.18 (1.26–3.79) ** 2.10 (1.03–4.30) * 0, 1, 2 b
RGS2 rs1152746 2.39 (1.05–5.41) * 2.63 (1.07–6.49) * 0, 1, 2 b

Logistic regression analysis was carried out with variables of age, gestational age, height, GNAS rs7121, GNAS rs3730168, and RGS2 rs1152746. * p-value < 0.05, ** p-value < 0.01. a Height < 160 cm was assigned to score 1 (0: ≥160 cm; 1: <160 cm). b Number of the variant allele was assigned to each score (0: GG, 1: GA, 2: AA for rs3730168; 0: CC, 1: CT, 2: TT for rs1152746).