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. 2022 Jun 18;14(6):1299. doi: 10.3390/pharmaceutics14061299

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of pH 1.2 HCl dissolution medium on different inert cores. (A) MCC spheres: Ethispheres^® (NPPharm Ltd., France); (B) DCPA spheres: PharSQ^® Spheres (Chemische Fabrik Budenheim, Budenheim, Germany; (C) Sugar core: Suglets^®; (Colorcon, Bazainville, France); (D) Isomalt cores: galenIQ^TM 980 (Beneo GmbH, Mannheim, Germany); (E) Tartaric acid cores: TAP (IPC Process-Center GmbH, Dresden, Germany) (F) Sodium bicarbonate core: (Umang Pharmatech Pvt Ltd., Thane, India) (Latter medium contains Phenolptalein solution R (Ph. Eur. 10) as an indicator).