Table 2.

Characteristic inert pellet core that can affect the quality of the final product.

Property	Consideration	Methods/Techniques/ Apparatus	Reference
Particle size and particle size distribution	final dosage form; processability (layering; blending), coating uniformity (drug load; polymer content)	sieve analysis; dynamic imaging analysis (DIA)	[54,55,56]
Solubility	processability, drug release	analytical measurement, image analysis	[48,57,58]
Surface area	processability (drug layer or coat thickness)	gas adsorption (BET); image analysis	[56]
Surface roughness	processability (drug layer or coat thickness)	image analysis 3D profilometer	[16]
Tensile strength	processability (fluidization, tableting)	Texture analyzer	[59]
Friability	processability	Ph.Eur. method	[60]