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M1 macrophages infected with rBCG-LTAK63 display higher secretion levels of inflammatory cytokines. M1 macrophages derived from 4 different donors were infected with rBCG-LTAK63 or BCG for 48 h and the supernatants were analyzed for cytokine production by Luminex and compared to uninfected control cells. Statistical significance was determined by RM—ANOVA (p ˂ 0.05). Significant differences were observed as indicated * p ˂ 0.05, ** p ˂ 0.01.
