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Schematic representation of the immune responses induced in human macrophages by infection with rBCG-LTAK63 that could correlate with the superior protection observed in a murine TB challenge model. Displayed are the differentially expressed genes (IFIT3, OAS3, CXCL9, TAP1, GBP1, TNIP1, SLAMF7, IL6, CD14, and HCK) and the production of cytokines (IL-12(p70), TNF-β, IL-15, MCP-3, and EGF).
