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Stability study of the optimized formulation R4.
| Time | Appearance | ET | MS | Contents % ± SD | |
|---|---|---|---|---|---|
| (Months) | h ± SD | g ± SD | SIT | MET | |
| 1 | White to off-white | 7.46 ± 3.76 | 24.54 ± 2.08 | 99.25 ± 0.54 | 99.20 ± 1.44 |
| 3 | White to off-white | 7.11 ± 2.19 | 23.68 ± 2.76 | 99.37 ± 1.01 | 98.59 ± 1.52 |
| 6 | White to off-white | 7.78 ± 3.33 | 26.37 ± 1.32 | 98.04 ± 1.23 | 98.31 ± 1.11 |
