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. 2022 May 30;15(6):685. doi: 10.3390/ph15060685

Figure 5.

Figure 5

Image-derived tumor uptake (mean % ID/g), tumor-to-muscle ratio (T/M), and tumor-to-blood ratio (T/B) of “state-of-the-art” pretargeting imaging agents: [64Cu]4 (PET 2 h p.i., n = 4), [111In]1 (SPECT 2 h p.i., n = 4), [18F]23 (PET 1 h p.i., n = 3), [18F]25 (PET 1 h p.i., n = 4), and [18F]27 (PET 1 h p.i., n = 5). Tumor uptake and ratios of all Tz agents in nude BALB/c mice bearing subcutaneous LS174T tumor xenografts pretreated with CC49-TCO (100 mg). Data are shown as mean ± standard error of mean (SEM). * Image-derived uptake in heart from SPECT and PET images used as a surrogate for blood.