Table 1.

Most common Glycyrrhiza species used as medicine.

Glycyrrhiza Species	Region	Specific Content	Ref
Glycyrrhiza uralensis (Glycyrrhiza radix)	China Northeastern Far east Russia	Owning the highest content of flavonoids (liquiritin, liquiritigenin, and isoliquiritin). Glycycoumarin only represented in G. uralensis.	[26,27,28,29,30,43]
		Isotrifloliol, licoricone, neoglycyrol, glycyrin, and licorisoflavan A in G. uralensis are higher.	[26]
		Glyinflanin D/G and licoflavone B are absent.	[44]
Glycyrrhiza glabra	Italy Spain China Russia Iran Central Asia	Owning the highest content of 18α-glycyrrhizic acid and 18β-glycyrrhizic acid.	[45]
		Higher content of saponins–licorice saponin K2/H2, licorice saponin B2, and licorice saponin G2/yunganoside K2. Quercetin absent in G. glabra.	[44,46,47]
		The highest content of apiosides (liquiritin apioside, isoliquiritin apioside, licuraside).	[30]
		Abundant 8-cyclized isoprenyl isoflavanes (e.g., glabridin and 4′-O-methylglabridin).	[29]
		Polysaccharide content in G. glabra is the highest.	[48,49]
Glycyrrhiza	China, Asia	Highest content of triterpene saponins.	[25,29]
inflata		Chalcone derivatives such as licochalcone (A, B, C, E), kanzonol C, and echinatin in G. inflata are higher.	[29,44,50]
		The content of quercetin is higher than that in G. uralensis.	[44,46,47]
		Highest content of prenylated chalcones.	[44]