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. 2022 May 25;15(6):657. doi: 10.3390/ph15060657

Table 2.

Skin permeation parameters after 24 h.

The Amount of Permeated Metformin
(µg/cm2)
The Steady-State Flux
(µg/cm2/h)
The Percent of Cumulative Permeation (%)
Formula #9 1224.27 ± 18.1 2.93 72
The optimum formula #13 1660 ± 32.4 3.61 97.6
Formula #16 1547 ± 21.7 3.26 91