Table 3.

Most frequent AEs related to Nivo+ICE (NICE) (n = 9)

AEs	Grade 1	Grade 2	Grade 3	Grade 4	All	Percentage
Nausea	6	1	0	0	7	78
Anemia	4	2	0	0	6	67
Alanine aminotransferase increased	5	0	0	0	5	56
Fatigue	5	0	0	0	5	56
Vomiting	5	0	0	0	5	56
Alkaline phosphatase increased	4	0	0	0	4	44
Aspartate aminotransferase increased	4	0	0	0	4	44
Hypertension	2	2	0	0	4	44
Hyponatremia	4	0	0	0	4	44
Hypophosphatemia	0	2	2	0	4	44
Neutrophil count decreased	1	1	0	2	4	44
Abdominal pain	3	0	0	0	3	33
Anxiety	3	0	0	0	3	33
Constipation	2	1	0	0	3	33
Creatinine increased	2	1	0	0	3	33
Hypoalbuminemia	3	0	0	0	3	33
Hypokalemia	3	0	0	0	3	33
Platelet count decreased	0	3	0	0	3	33
Edema limbs	2	0	0	0	2	22
Hiccups	1	1	0	0	2	22
Hyperglycemia	1	1	0	0	2	22
Rash maculopapular	2	0	0	0	2	22
Sinus tachycardia	2	0	0	0	2	22
White blood cell decreased	0	1	1	0	2	22