Table 1.
IC50 value of cholinesterase, BACE1, and MAO inhibitions.
| Compounds | IC50 Value | Reference |
|---|---|---|
| Cholinesterases Inhibition | ||
| Sulfated polysaccharides extracted from Ulva lactuca L. | 106.93 µg/mL (AChE)/93.45 µg/mL (BChE) | [203] |
| Glycoprotein isolated from U. pinnatifida | 63.56 μg/mL (AChE)/99.03 μg/mL (BChE) | [204] |
| Fucoxanthin | 81.2 µM (AChE) | [205] |
| Phlorotannin 974-B | 1.95 µM (AChE)/3.26 μM (BChE) | [206] |
| α-Linolenic acid | 12.50 μg/mL (AChE)/15.89 μg/mL (BChE) | [207] |
| BACE 1 Inhibition | ||
| Glycoprotein isolated from U. pinnatifida | 73.35 μg/mL | [204] |
| Fucoxanthin | 5.31 μM | [208] |
| Fucosterol | 64.12 μM | [208] |
| Dioxinodehydroeckol | 5.35 μM | [209] |
| Eckol | 12.20 μM | [209] |
| Phlorofurofucoeckol A | 2.13 μM | [209] |
| Dieckol | 2.21 μM | [209] |
| Triphloroethol A | 11.68 μM | [209] |
| 7-Phloroethol | 8.59 μM | [209] |
| Fucofuroeckol-b | 16.1 μM | [210] |
| MAO Inhibition | ||
| Fucoxanthin | 197.41 μM (MAO-A)/211.12 μM (MAO-B) | [211] |
| Eckol | 7.20 μM (MAO-A)/83.44 μM (MAO-B) | [212,213] |
| Dieckol | 11.43 μM (MAO-A)/43.42 μM (MAO-B) | [212,213] |
| Phlorofucofuroeckol-A | 9.22 μM (MAO-A)/4.89 μM (MAO-B) | [213] |