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. 2022 May 24;20(6):342. doi: 10.3390/md20060342

Table 2.

Seaweeds polysaccharides and their roles in foods and cosmeceuticals.

Component Species Models Doses MW Activity Results References
Carrageenan Padina tetrastromatic Paw edema in rats 20 mg kg−1 25 kDa Anti-inflammation COX-2 and iNOS inhibitions [49]
Fucoidan Fucus vesiculosus Human malignant
melanoma cells
100–400 µg mL−1 60 kDa Anticancer activity Inhibit cell proliferation [50]
B16 murine melanoma
cells
550 µg mL−1 - Anti-melanogenic Inhibit tyrosinase and melanin [51]
Ulvans Ulva sp. Human dermal fibroblast 100 and 500 µg mL−1 4–57 kDa Anti-aging Increase hyaluronan production [52]
Laminaran Laminaria japonica In vitro 15 mg mL−1 250 kDa antioxidant
activity
ROS scavenging potential [53]
Fucoidan Chnoospora minima RAW macrophages 27.82 µg mL−1 60 kDa Anti-inflammation Inhibition of LPS-induced NO
production, iNOS, COX-2, and PGE2
levels
[54]
Fucoidan Sargassum
hemiphyllum
RAW 264.7 macrophage
cells
dose-dependent manner - Anti-inflammation Inhibit LPS-induced inflammatory
response
[55]
Fucoidan Sargassum
hemiphyllum
B16 melanoma cells dose-dependent manner - Anticancer Activation of caspase-3 [56]