Table 2.
Component | Species | Models | Doses | MW | Activity | Results | References |
---|---|---|---|---|---|---|---|
Carrageenan | Padina tetrastromatic | Paw edema in rats | 20 mg kg−1 | 25 kDa | Anti-inflammation | COX-2 and iNOS inhibitions | [49] |
Fucoidan | Fucus vesiculosus | Human malignant melanoma cells |
100–400 µg mL−1 | 60 kDa | Anticancer activity | Inhibit cell proliferation | [50] |
B16 murine melanoma cells |
550 µg mL−1 | - | Anti-melanogenic | Inhibit tyrosinase and melanin | [51] | ||
Ulvans | Ulva sp. | Human dermal fibroblast | 100 and 500 µg mL−1 | 4–57 kDa | Anti-aging | Increase hyaluronan production | [52] |
Laminaran | Laminaria japonica | In vitro | 15 mg mL−1 | 250 kDa | antioxidant activity |
ROS scavenging potential | [53] |
Fucoidan | Chnoospora minima | RAW macrophages | 27.82 µg mL−1 | 60 kDa | Anti-inflammation | Inhibition of LPS-induced NO production, iNOS, COX-2, and PGE2 levels |
[54] |
Fucoidan |
Sargassum
hemiphyllum |
RAW 264.7 macrophage cells |
dose-dependent manner | - | Anti-inflammation | Inhibit LPS-induced inflammatory response |
[55] |
Fucoidan |
Sargassum
hemiphyllum |
B16 melanoma cells | dose-dependent manner | - | Anticancer | Activation of caspase-3 | [56] |