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. 2022 May 24;20(6):342. doi: 10.3390/md20060342

Table 11.

The potential pharmacological activity of brown, red and green seaweeds.

Component Properties/Activities Seaweed Doses Models References
Fucoxanthins Antitumoral activity on lung
cancer cells
Laminaria japonica 12.5–100 μM Female and male (1:1 ratio) BALB/c nude mice (18–20 g; 6–8 weeks of age) [341]
Antitumoral activity on MCF-7, HepG-2, HCT-116 cells Colpomenia sinuosa, Sargassum prismaticum 100 and 200 mg/kg Paracetamol-administered rats (one dose of 1 g/kg) [342]
Antitumoral activity on SiHa, Malme-3M cells Undaria pinnatifida 1.5625, 6.25, 12.5, 25, 50, 80, 100 µM Human cell lines [343]
Antimicrobial activity Cladosiphon okamuranus 2–2000 µg/mL. Helicobacter pylori [344]
Antimicrobial activity Laminaria japonica 2, 3, 4, 5, 6, 7, and 7.5 mg/mL Staphylococcus aureus, Escherichia coli [345]
Antimicrobial activity Fucus vesiculosus 2, 4, 6, 8 and 10 mg/mL Staphylococcus aureus,
Bacillus licheniformis, Escherichia coli, Staphylococcus epidermidis
[346]
Antiviral activity against ECHO-1, HIV-1, HSV-1, HSV-2 Fucus evanescens 200 μg/mL Female outbred mice (16–20 g) [347]
Sulfate polysaccharide Antiviral activity against
HSV-1, HVS-2
Sargassum patens 0.78–12.5 μg/mL Vero cells (African green monkey kidney cell line) [348]
Anti-obesity, antidiabetic activities Gracilaria lemaneiformis 5–10% Seaweed powder Dawley laboratory rats (4 to 5 months old, 250–300 g) [349]
Phloroglucinol Anti-inflammatory activity Ecklonia cava 1, 5, 10, 50
100 µM
HT1080 and
RAW264.7 cells
[350]