Table 1.
Distribution of Sosuga virus nucleoprotein antigen in selected tissues from SOSV-infected Egyptian rousette bats euthanized at 3, 6, 9 and 21 DPI.
DPI | Bat ID | Small Intestines | Salivary Gland | AxLN | Spleen | Large Intestinal GALT |
---|---|---|---|---|---|---|
3 | 283936 | NP | - | + | - | NP |
284049 | - | - | + | - | - | |
284459 | - | - | - | - | - | |
6 | 284509 | - | - | ++ | - | - |
284899 | + | + | + | ++ | - | |
285146 | - | - | - | - | - | |
9 | 287014 | - | - | - | - | - |
287253 | - | - | - | + | - | |
287756 | + | - | + | + | + | |
21 | 289338 | - | + | - | - | - |
289953 * | + | - | + | + | + | |
290040 | - | - | + | - | - | |
Control | 290195 | - | - | NP | NP | - |
290494 | - | - | - | - | - | |
290631 | - | - | - | - | - |
Abbreviations: DPI = days post-inoculation, AxLN = axillary lymph node, GALT = large intestinal gastrointestinal-associated lymphoid tissue, NP = not performed due to tissue limitations. IHC Scores: - = no staining, + = rare staining (<1 cell per 400× field), ++ = moderate staining (>2 cells per 400× field). * Indicates the supershedder bat identified during the serial euthanasia study [27].