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. 2022 Jun 1;12(6):508. doi: 10.3390/metabo12060508

Table 3.

Statically significant metabolites among the prediabetic MetS group and the controls.

t.Stat p.Value FDR Fold Change
Hippuric acid −4.997 7.23 × 10−6 3.41 × 10−5 168.99
L-Sorbose −6.5991 2.34 × 10−8 1.54 × 10−7 112.29
5-Hydroxy-L-tryptophan −14.973 3.26 × 10−21 3.23 × 10−19 7.8145
Homoveratric acid −13.381 3.46 × 10−19 1.14 × 10−17 6.7333
Indolelactic acid −8.0659 8.53 × 10−11 9.39 × 10−10 5.7961
1,3-Dimethyluric acid −7.1566 1.76 × 10−9 1.58 × 10−8 5.7356
L-Aspartyl-L-phenylalanine −6.2668 2.84 × 10−8 1.76 × 10−7 4.8287
L-Glutamine −7.0562 3.24 × 10−9 2.47 × 10−8 4.7812
Alpha-Tocopherol −4.1864 9.14 × 10−5 0.00037703 3.2137
Indole-3-carbinol −4.082 0.00010219 0.00038912 1.8178
Glycerophosphocholine −11.298 2.17 × 10−19 1.07 × 10−17 1.7227
Nonadecanoic acid −3.5226 0.00079411 0.002536 1.5918
3-Hexenedioic acid −2.9064 0.0047055 0.010587 1.5583
Medroxyprogesterone −3.3856 0.0010441 0.0031729 1.5147
Heptadecanoic acid −3.8583 0.00025945 0.00095133 1.4928
Trimethylamine −8.3473 2.96 × 10−13 4.19 × 10−12 1.4759
Quinaldic acid −3.17 0.0024236 0.0063142 1.4694
3-Hydroxymethylglutaric acid −2.8211 0.0063286 0.013923 1.4489
L-Norleucine −2.6868 0.0085954 0.017728 1.355
L-Glutamic acid −5.3425 5.02 × 10−7 2.62 × 10−6 1.2829
2-Furoylglycine −4.6727 8.55 × 10−6 3.85 × 10−5 1.2707
Elaidic acid −4.7976 5.15 × 10−6 2.55 × 10−5 1.2702
Benzoic acid −3.2383 0.001675 0.0047047 1.2563
o-Tyrosine −2.9137 0.0045066 0.010587 1.2511
m-Coumaric acid −3.0439 0.0029627 0.0075208 1.2423
Pantothenic acid −3.3059 0.0013618 0.0039652 1.238
2,4-Diaminobutyric acid −3.1673 0.0020146 0.0053904 1.2297
L-Proline −2.7595 0.0070984 0.014952 1.2077
Allantoic acid −3.2264 0.0017108 0.0047047 1.2058
Pipecolic acid −2.3124 0.022748 0.041705 1.2013
L-Carnitine −2.4289 0.017903 0.034085 1.1728
Creatinine −3.0407 0.0031613 0.0076335 1.1642
m-Aminobenzoic acid −2.5326 0.012834 0.025931 1.1603
Indole −2.894 0.0046922 0.010587 1.1492
L-Histidine −2.3403 0.021428 0.040027 1.1351
3-Methylindole −3.587 0.00051176 0.0016888 1.1249
Cinnamic acid −2.4588 0.015506 0.030701 1.1234
Phenylacetic acid −2.756 0.006908 0.014867 1.0948
L-Tryptophan −2.2723 0.025179 0.044513 1.0784
Benzamide 3.0269 0.0030779 0.0076178 0.89678
5-Hydroxylysine 2.3014 0.023624 0.042523 0.84997
Pregnenolone sulfate 2.4517 0.015934 0.030931 0.79827
Sphingosine 2.2348 0.027463 0.047699 0.79163
Androsterone 3.384 0.0010576 0.0031729 0.70978
Saccharopine 3.7427 0.00029123 0.0010297 0.65817
Nutriacholic acid 4.4071 3.36 × 10−5 0.00014474 0.59816
Thyroxine 4.0722 9.57 × 10−5 0.00037908 0.59602
4-Aminohippuric acid 6.6679 2.82 × 10−9 2.33 × 10−8 0.51509
Glycyl-L-leucine 6.9782 2.37 × 10−10 2.34 × 10−9 0.49622
Vitamin D3 5.7192 1.93 × 10−7 1.06 × 10−6 0.47169
Urea 10.172 5.50 × 10−15 1.09 × 10−13 0.41933
Sphinganine 10.711 1.67 × 10−18 4.12 × 10−17 0.31225
Acetic acid 6.5618 1.11 × 10−8 7.85 × 10−8 0.2382
3-Indolepropionic acid 3.6696 0.00049507 0.0016888 0.18522
3,4,5-Trimethoxycinnamic acid 6.3521 3.30 × 10−8 1.92 × 10−7 0.1117
9-Methyluric acid 9.4247 1.56 × 10−13 2.58 × 10−12 0.059596
3-Methylxanthine 8.2614 1.96 × 10−11 2.42 × 10−10 0.026165