The genomic organization of a PEDV and its structural (S, E, M, and N), non-structural (nsp1–16), and accessory (ORF3) proteins. The green and red bars located at the 5′ UTR or upstream of each ORF represent the leader TRS and body TRS regions. Abbreviations: a number for pp1a and pp1ab indicate the non-structural proteins 1–16. PLpro: Papain-like protease; 3CLpro: chymotrypsin-like protease; RdRp: RNA-dependent RNA polymerase; ExoN: Exoribonuclease; N7-MTase: N7-methyltransferase; EndoU: endoribonuclease; 2′-O-MTase: 2′-O methyltransferase; S: spike; E: envelop; M: membrane; and N: nucleocapsid.