Table 2.
Estimated mean changes in anthropometric, serologic, bioimpedance, and ultrasonographic parameters over the study period (T3 and T6).
Parameters | Time | ||
---|---|---|---|
T0 | Variation at T3 | Variation at T6 | |
Body weight (kg) | 103.96 ± 3.03 | −7.83 ± 0.72 ** | −9.89 ± 0.99 ** # |
Body mass index (kg/m2) | 38.81 ± 1.18 | −3.05 ± 0.30 ** | −3.36 ± 0.42 ** |
Waist circumference (cm) | 123.53 ± 2.24 | −6.32 ± 1.12 ** | −7.31 ± 1.15 ** |
Fasting glycemia (mg/dL) | 129.95 ± 5.71 | −15.57 ± 4.41 ** | −23.56 ± 4.45 ** ## |
HbA1c (mmol/mol) | 52.86 ± 3.36 | −10.72 ± 2.80 ** | −11.16 ± 2.99 ** |
Serum creatinine (mg/dL) | 0.88 ± 0.04 | 0.03 ± 0.03 | 0.01 ± 0.03 |
eGFR (mL/min/1.73 m2) | 87.85 ± 3.57 | 0.85 ± 2.55 | −2.02 ± 2.52 |
Fasting serum insulin (mUI/L) | 22.59 ± 2.46 | −0.76 ± 3.17 | −5.22 ± 2.16 * |
Fasting serum C-peptide (ng/mL) | 3.72 ± 0.24 | 0.08 ± 0.29 | −0.13 ± 0.27 |
HOMA-IR index | 6.88 ± 0.77 | −1.22 ± 1.06 | −2.62 ± 0.79 ** |
Visceral adipose tissue (L) | 5.74 ± 0.45 | −0.55 ± 0.27 * | −0.95 ± 0.24 * # |
Fat mass index (kg/m2) | 17.10 ± 0.99 | −2.19 ± 0.46 ** | −3.04 ± 0.43 ** # |
Fat-free mass index (kg/m2) | 21.45 ± 0.47 | −0.61 ± 0.24 * | −0.74 ± 0.17 ** |
Skeletal muscle mass (kg) | 28.16 ± 0.98 | −1.31 ± 0.37 ** | −1.53 ± 0.36 ** |
Skeletal muscle index (kg/m2) | 10.36 ± 0.27 | −0.52 ± 0.14 ** | −0.51 ± 0.14 ** |
HG (kg) | 32.49 ± 1.64 | 0.49 ± 1.75 | 0.76 ± 1.26 |
MQI (kg/kg) | 1.06 ± 0.09 | 0.16 ± 0.09 | 0.17 ± 0.08 |
Total body water (L) | 42.95 ± 1.39 | −0.20 ± 0.79 | −0.87 ± 1.13 |
Extracellular body water (L) | 19.45 ± 0.56 | −0.10 ± 0.32 | −0.41 ± 0.48 |
ECW to TBW ratio | 45.6 ± 0.41 | −0.24 ± 0.36 | 0.00 ± 0.35 |
Phase angle (°) | 5.76 ± 0.12 | −0.15 ± 0.10 | −0.21 ± 0.10 |
US-VAT (cm) | 6.93 ± 0.39 | −1.45 ± 0.23 ** | −1.49 ± 0.33 ** |
Models for each parameter are expressed as mean ± S.E. at T0 and mean variation ± S.E. at T3 and T6. HbA1c: glycated hemoglobin; eGFR: estimated glomerular filtration rate; HOMA-IR: homeostatic model assessment for insulin resistance; HG: hand grip; MQI: muscle quality index; ECW: extracellular body water; TBW: total body water; US-VAT: ultrasonographic visceral adipose tissue. Variation versus T0: * p < 0.05; ** p < 0.01. Variation versus T3: # p < 0.05; ## p < 0.01.