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Schematic illustration of construction of SIM@HA-MSN for atherosclerosis management. (A) Scheme of fabrication process and administration route of SIM@HA-MSN. (B) Illustration of SIM@HA-MSN therapy which can potentially alleviate atherosclerosis through long circulating, enzyme-responsive drug release, macrophage targeting, and anti-inflammatory and anti-foaming effects. (Created by Biorender).
