Table 5.
Comparison of brain structures between Recent-SA, Remote-SA, and Lifetime-SI only analyzed in Study 2.
| Region of Interest | Recent-SA (n = 11) Mean ± SD | Remote-SA (n = 11) Mean ± SD | Lifetime-SI (n = 12) Mean ± SD | p-value adjusted |
|---|---|---|---|---|
| Cortical thickness | ||||
| Caudal ACC | 5.40 ± 0.23 | 5.40 ± 0.47 | 5.29 ± 0.56 | p=.818 |
| IFG | 15.00 ± 0.51 | 14.94 ± 1.25 | 14.52 ± 1.08 | p=.822 |
| Inferior temporal | 5.06 ± 0.25 | 5.15 ± 0.39 | 5.02 ± 0.39 | p=.760 |
| Insula | 6.00 ± 0.24 | 5.99 ± 0.44 | 5.86 ± 0.37 | p=.943 |
| Lateral OFC | 5.02 ± 0.24 | 5.11 ± 0.42 | 4.96 ± 0.32 | p=.736 |
| Medial OFC | 4.62 ± 0.23 | 4.81 ± 0.46 | 4.66 ± 0.30 | p=.345 |
| Middle temporal | 5.38 ± 0.28 | 5.49 ± 0.39 | 5.17 ± 0.36 | p=.364 |
| Superior frontal | 5.42 ± 0.24 | 5.31 ± 0.42 | 5.18 ± 0.36 | p=.419 |
| Superior parietal | 4.32 ± 0.19 | 4.35 ± 0.32 | 4.01 ± 0.31 | p=.024 |
| Superior temporal | 5.39 ± 0.25 | 5.45 ± 0.38 | 5.24 ± 0.28 | p=.592 |
| Surface area | ||||
| Caudal ACC | 1359.36 ± 209.15 | 1530.45 ± 337.42 | 1417.67 ± 396.03 | p=.430 |
| IFG | 6266.36 ± 671.27 | 7062.18 ± 1188.93 | 7056.17 ± 933.93 | p=.141 |
| Inferior temporal | 5878.91 ± 639.32 | 6323.64 ± 1250.79 | 6070.75 ± 914.19 | p=.411 |
| Insula | 3747.09 ± 370.48 | 4021.91 ± 577.48 | 4290.58 ± 629.89 | p=.260 |
| Lateral OFC | 4682.55 ± 463.46 | 4900.55 ± 872.49 | 4988.33 ± 688.79 | p=.806 |
| Medial OFC | 3307.73 ± 390.57 | 3488.18 ± 653.03 | 3620.25 ± 462.98 | p=.566 |
| Middle temporal | 5845.55 ± 573.91 | 6262.09 ± 1230.60 | 6197.25 ± 875.65 | p=.589 |
| Superior frontal | 12,914.64 ± 1174.78 | 13,530.45 ± 2093.53 | 14,231.25 ± 1654.05 | p=.458 |
| Superior parietal | 9787.27 ± 1280.46 | 10,564.73 ± 1155.82 | 10,661.00 ± 1338.10 | p=.322 |
| Superior temporal | 6611.27 ± 381.47 | 7048.45 ± 1146.12 | 7254.33 ± 878.86 | p=.367 |
| Subcortical volume | ||||
| Caudate | 7257.12 ± 599.28 | 7188.78 ± 1207.95 | 7426.52 ± 1138.37 | p=.995 |
| Hippocampus | 7604.11 ± 578.20 | 7723.02 ± 1149.66 | 8049.52 ± 958.42 | p=.779 |
| Putamen | 11,098.31 ± 802.74 | 11,931.23 ± 1749.28 | 11,637.27 ± 1600.05 | p=.212 |
| Thalamus | 12,944.33 ± 864.88 | 13,390.44 ± 2022.57 | 13,941.46 ± 2344.56 | p=.498 |
| Nucleus Accumbens | 1411.95 ± 206.48 | 1406.87 ± 283.40 | 1420.84 ± 266.07 | p=.967 |
ACC: anterior cingulate cortex; IFG: inferior frontal gyrus; OFC = orbitofrontal cortex.
Cortical thickness is expressed in millimeters; Surface area is expressed in millimeters2; Volume is expressed in millimeters3.