Table 2.

Hypothesized impacts of pregnancy adaptations and complications on autonomic metrics.

Physiologic or Pathologic Change in Pregnancy	Temperature	HR	HRV	Emotional State
1st Trimester rising progesterone	elevate [34]	elevate [35]	lower [35]	fatigue [36]
Suboptimal progesterone production prior to miscarriage [21]	relatively lower [137]	relatively lower, hypothesized [138]	relatively elevated, hypothesized [139]	?
Reduced plasma volume increase preceding preeclampsia [107]	relatively elevated, hypothesized	relatively elevated [16,43]	relatively lower [44]	anxiety [140]
Peripartum depression	circadian destabilization, reduced amplitude, hypothesized	relatively elevated, hypothesized	relatively lower, hypothesized	depressive symptom onset