CPIC |
Clinical Pharmacogenetics Implementation Consortium |
COX-1 |
Cyclooxygenase 1 |
COX-2 |
Cyclooxygenase 2 |
EM |
Extensive metabolizer |
GI |
Gastrointestinal |
IM |
Intermediate metabolizer |
NM |
Normal metabolizer |
NSAIDs |
Nonsteroidal anti-inflammatory drugs |
PM |
Poor metabolizer |
RM |
Rapid metabolizer |
SNPs |
Single-nucleotide polymorphisms |
SNRIs |
Serotonin-norepinephrine reuptake inhibitors |
SSRIs |
Selective serotonin reuptake inhibitors |
Tmax |
Time of the maximum plasma concentration |
TNF-α |
Tumor necrosis factor α |
TCAs |
Tricyclic antidepressants |
UGTs |
Uridine 5′-diphospho-glucuronosyltransferase |
UGIB |
Upper gastrointestinal bleeding |
UM |
Ultra-rapid metabolizer |
VKOR |
Vitamin K epoxide reductase |
ECG |
Electrocardiography |
Ads |
Antidepressants |